DUBLIN-4: a global, double-blind Phase 3 registrational confirmatory trial evaluating Plinabulin + docetaxel vs. docetaxel in non-squamous EGFR wild-type NSCLC after progression on anti-PD-(L)1 and chemotherapy
Latest Information Update: 23 Dec 2025
At a glance
- Drugs Docetaxel (Primary) ; Plinabulin (Primary)
- Indications Non-small cell lung cancer
- Focus Registrational; Therapeutic Use
Most Recent Events
- 23 Dec 2025 New trial record
- 11 Dec 2025 According to a BeyondSpring Pharmaceuticals media release, plans to initiate a global Phase 3 DUBLIN-4 trial following its End-of-Phase 2 meeting with the U.S. FDA.
- 11 Dec 2025 According to a BeyondSpring Pharmaceuticals media release, DUBLIN-4, together with DUBLIN-3, is expected to support a future NDA submission in non-squamous EGFR wild-type NSCLC following progression on anti-PD-(L)1 therapy.