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A Single-Arm, Phase II Study of Perioperative Zimberelimab + Domvanalimab and Neoadjuvant Chemotherapy in Locally Advanced, Resectable, Gastroesophageal Adenocarcinoma

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Trial Profile

A Single-Arm, Phase II Study of Perioperative Zimberelimab + Domvanalimab and Neoadjuvant Chemotherapy in Locally Advanced, Resectable, Gastroesophageal Adenocarcinoma

Status: Withdrawn prior to enrolment
Phase of Trial: Phase II

Latest Information Update: 29 Dec 2025

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At a glance

  • Drugs Domvanalimab (Primary) ; Zimberelimab (Primary) ; Docetaxel; Fluorouracil; Folinic acid; Oxaliplatin
  • Indications Adenocarcinoma; Gastric cancer; Oesophageal cancer
  • Focus Therapeutic Use

Most Recent Events

  • 26 Dec 2025 Status changed from not yet recruiting to withdrawn prior to enrolment.
  • 23 Dec 2025 New trial record

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