Trial Profile

An Open-label, Multi-center, Phase I/II Study of GVV858 as a Single Agent and in Combination With Endocrine Therapy in Patients With Advanced Hormone Receptor Positive, HER2- Negative Breast Cancer and Other Advanced Solid Tumors

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 24 Dec 2025

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At a glance

Drugs Fulvestrant (Primary) ; GVV 858 (Primary) ; Letrozole (Primary)
Indications Advanced breast cancer; HER2 negative breast cancer; HER2 positive breast cancer; Solid tumours
Focus Adverse reactions; First in man
Sponsors Novartis Pharmaceuticals

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