Trial Profile

A Phase 1b/2 Trial Investigating the Safety and Efficacy of Oral AMXT 1501 and Oral DFMO in Combination With Standard of Care in Patients With Advanced Solid Tumors Who Progressed After Prior Therapies

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 16 Jan 2026

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At a glance

Drugs AMXT 1501 (Primary) ; Capivasertib (Primary) ; Eflornithine (Primary) ; Fulvestrant (Primary) ; Pembrolizumab (Primary)
Indications HER2 negative breast cancer; Malignant melanoma; Solid tumours
Focus Adverse reactions; Therapeutic Use
Sponsors Aminex Therapeutics

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