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A Cohort Study to Investigate the Risk of Liver Disorder of Livmarli Oral Solution in Patients With Japan Alagille Syndrome (ALGS) and Progressive Familial Intrahepatic Cholestasis (PFIC) Registered in the Comprehensive and Informative Registry System for Childhood Liver Disease (CIRCLe)

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Trial Profile

A Cohort Study to Investigate the Risk of Liver Disorder of Livmarli Oral Solution in Patients With Japan Alagille Syndrome (ALGS) and Progressive Familial Intrahepatic Cholestasis (PFIC) Registered in the Comprehensive and Informative Registry System for Childhood Liver Disease (CIRCLe)

Status: Recruiting
Phase of Trial: Phase IV

Latest Information Update: 23 Feb 2026

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At a glance

  • Drugs Maralixibat (Primary)
  • Indications Alagille syndrome; Intrahepatic cholestasis
  • Focus Therapeutic Use
  • Sponsors Takeda

Most Recent Events

  • 20 Feb 2026 Status changed from not yet recruiting to recruiting.
  • 25 Dec 2025 New trial record

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