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LATITUDE - A Phase 3, Randomized, Open-Label, 3-Cohort, 2-Period, 2-Sequence, Crossover Trial to Evaluate the Pharmacokinetics, Safety, and Efficacy of Oral Arsenic Trioxide Versus Intravenous Arsenic Trioxide for Consolidation Therapy in Participants With Newly Diagnosed, Non-High-Risk, Acute Promyelocytic Leukemia

Trial Profile

LATITUDE - A Phase 3, Randomized, Open-Label, 3-Cohort, 2-Period, 2-Sequence, Crossover Trial to Evaluate the Pharmacokinetics, Safety, and Efficacy of Oral Arsenic Trioxide Versus Intravenous Arsenic Trioxide for Consolidation Therapy in Participants With Newly Diagnosed, Non-High-Risk, Acute Promyelocytic Leukemia

Status: Not yet recruiting
Phase of Trial: Phase III

Latest Information Update: 26 Dec 2025

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At a glance

  • Drugs Arsenic trioxide (Primary) ; Arsenic trioxide (Primary) ; Tretinoin
  • Indications Acute promyelocytic leukaemia
  • Focus Pharmacokinetics; Registrational
  • Acronyms LATITUDE
  • Sponsors SDK Therapeutics

Most Recent Events

  • 26 Dec 2025 New trial record

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