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A Phase II, Multi-site, Open-label Trial Evaluating the Safety and Efficacy of BNT327 and Bevacizumab as Monotherapy and BNT327 in Combination With Temozolomide in Patients With Recurrent Glioblastoma

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Trial Profile

A Phase II, Multi-site, Open-label Trial Evaluating the Safety and Efficacy of BNT327 and Bevacizumab as Monotherapy and BNT327 in Combination With Temozolomide in Patients With Recurrent Glioblastoma

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 02 Feb 2026

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At a glance

  • Drugs Bevacizumab (Primary) ; Pumitamig (Primary) ; Temozolomide (Primary)
  • Indications Glioblastoma
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors BioNTech

Most Recent Events

  • 30 Jan 2026 Status changed from not yet recruiting to recruiting.
  • 26 Dec 2025 New trial record

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