Trial Profile

A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Prospective, Investigator-Initiated Trial to Assess the Efficacy, Safety, and Pharmacokinetics of Epetraborole in Patients With Mycobacterium Abscessus Lung Disease: REBOUND Study

Status: Not yet recruiting

Phase of Trial: Phase II

Latest Information Update: 27 Feb 2026

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At a glance

16 Jan 2026 Planned initiation date changed from 1 Jan 2026 to 1 Feb 2026.
12 Jan 2026 According to AN2 Therapeutics media release, the USFDA has cleared the IND application for this Investigator-Initiated trial (IIT). This study will be led by Dr. Kevin Winthrop, Professor of Public Health and Infectious Diseases at OHSU, in collaboration with other investigators across 10-15 sites in the USA. Positive data from this study could establish human proof of concept.
30 Dec 2025 New trial record

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