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Phase IIb, Randomized, Active-Controlled, Parallel-Group, Multicenter Clinical Study to Evaluate the Efficacy and Safety of AST-3424 in Patients With AKR1C3-High Expressing Advanced Hepatocellular Carcinoma Who Progressed After Systemic Therapy With Immune Checkpoint Inhibitors

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Trial Profile

Phase IIb, Randomized, Active-Controlled, Parallel-Group, Multicenter Clinical Study to Evaluate the Efficacy and Safety of AST-3424 in Patients With AKR1C3-High Expressing Advanced Hepatocellular Carcinoma Who Progressed After Systemic Therapy With Immune Checkpoint Inhibitors

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 05 Jan 2026

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At a glance

  • Drugs OBI 3424 (Primary) ; Regorafenib
  • Indications Carcinoma; Liver cancer
  • Focus Therapeutic Use
  • Sponsors Zhejiang Hisun Pharmaceutical

Most Recent Events

  • 05 Jan 2026 New trial record

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