Trial Profile

A Phase 1b, Multicenter, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL628 in Participants With Early Alzheimer's Disease

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 26 Feb 2026

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At a glance

23 Feb 2026 Status changed from not yet recruiting to recruiting.
14 Jan 2026 New trial record
06 Jan 2026 According to Denali Therapeutics media release, announced that the Clinical Trial Application (CTA) for the Phase 1b study of DNL628 has been approved and study start-up activities are underway.

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