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A Phase I First-in-human Clinical Trial to Evaluate the Safety, Pharmacokinetics, and Antiviral Activity of the Broadly Neutralizing Antibody BNT351 in Adults Living Without and With HIV

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Trial Profile

A Phase I First-in-human Clinical Trial to Evaluate the Safety, Pharmacokinetics, and Antiviral Activity of the Broadly Neutralizing Antibody BNT351 in Adults Living Without and With HIV

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 23 Feb 2026

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At a glance

  • Drugs BNT 351 (Primary) ; BNT 351 (Primary)
  • Indications HIV-1 infections
  • Focus Adverse reactions; First in man; Pharmacokinetics; Proof of concept; Therapeutic Use
  • Sponsors BioNTech

Most Recent Events

  • 19 Feb 2026 Status changed from not yet recruiting to recruiting.
  • 21 Jan 2026 New trial record

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