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UNLOCK - EPIBREAST, a Phase II Study of Prifetrastat (PF-07248144), a KAT6 Inhibitor, Plus Fulvestrant for Advanced HR+/HER2- Breast Cancer, With Biomarkers Analyses

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Trial Profile

UNLOCK - EPIBREAST, a Phase II Study of Prifetrastat (PF-07248144), a KAT6 Inhibitor, Plus Fulvestrant for Advanced HR+/HER2- Breast Cancer, With Biomarkers Analyses

Status: Not yet recruiting
Phase of Trial: Phase II

Latest Information Update: 21 Jan 2026

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At a glance

  • Drugs Fulvestrant (Primary) ; Prifetrastat (Primary) ; Goserelin; Leuprorelin; Triptorelin
  • Indications Advanced breast cancer; HER2 negative breast cancer; Male breast cancer
  • Focus Therapeutic Use
  • Acronyms EPIBREAST

Most Recent Events

  • 21 Jan 2026 New trial record

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