Trial Profile

A Randomized, Multicenter, Open-label Clinical Study Using Peripheral Blood Circulating Tumor DNA to Evaluate the Efficacy of Preoperative Treatment With Pyrotinib + Trastuzumab + Docetaxel Versus Pertuzumab + Trastuzumab + Docetaxel in Early or Locally Advanced HER2-positive Breast Cancer

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 21 Jan 2026

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At a glance

Drugs Docetaxel (Primary) ; Pyrotinib (Primary) ; Trastuzumab (Primary) ; Pertuzumab
Indications Advanced breast cancer; Early breast cancer; HER2 negative breast cancer
Focus Pharmacodynamics

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