Trial Profile

Phase II Double-Blinded Placebo-Controlled Randomized Trial of CSF-1R Inhibitor, Axatilimab for Prevention of Acute and Chronic GVHD After HLA-Matched Related and Unrelated Donor Allogeneic Stem Cell Transplantation (ABRAXAS)

Status: Not yet recruiting

Phase of Trial: Phase II

Latest Information Update: 30 Jan 2026

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At a glance

Drugs Axatilimab (Primary) ; Cyclophosphamide; Mycophenolate mofetil; Mycophenolate mofetil; Tacrolimus
Indications Graft-versus-host disease
Focus Therapeutic Use
Acronyms ABRAXAS
Sponsors Mayo Clinic

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