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CLeAR: Pilot Study to Evaluate the Efficacy of Cemiplimab (PD-1 Inhibition) With or Without Fianlimab (LAG-3 Inhibition) After Y90 Radioembolization in Patients With Hepatocellular Carcinoma

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Trial Profile

CLeAR: Pilot Study to Evaluate the Efficacy of Cemiplimab (PD-1 Inhibition) With or Without Fianlimab (LAG-3 Inhibition) After Y90 Radioembolization in Patients With Hepatocellular Carcinoma

Status: Not yet recruiting
Phase of Trial: Phase I

Latest Information Update: 03 Feb 2026

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At a glance

  • Drugs Cemiplimab (Primary) ; Fianlimab (Primary)
  • Indications Liver cancer; Solid tumours
  • Focus Therapeutic Use
  • Acronyms CLeAR
  • Sponsors Regeneron Pharmaceuticals

Most Recent Events

  • 03 Feb 2026 New trial record

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