Trial Profile

Randomized Phase 2 Study of Second-line Chemotherapy Comparing FOLFIRI + Ivonescimab Versus FOLFIRI + Bevacizumab in Microsatellite Stable (MSS)/ Proficient MisMatch Repair (pMMR) BRAF Wild Type (BRAFwt) Advanced Colorectal Cancer (mCRC) Without Liver Metastases

Status: Not yet recruiting

Phase of Trial: Phase II

Latest Information Update: 03 Feb 2026

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At a glance

Drugs Fluorouracil (Primary) ; Folinic acid (Primary) ; Irinotecan (Primary) ; Ivonescimab (Primary) ; Bevacizumab
Indications Colorectal cancer
Focus Therapeutic Use
Acronyms COLIBRI-GI

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