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A Phase I, Open-label, Two-part, Fixed-sequence Drug Interaction Study to Evaluate the Effects of Concomitant Use of the CYP3A4 Inhibitor Itraconazole or the CYP3A4 Inducer Rifampin on the Pharmacokinetics of Rocbrutinib in Healthy Subjects

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Trial Profile

A Phase I, Open-label, Two-part, Fixed-sequence Drug Interaction Study to Evaluate the Effects of Concomitant Use of the CYP3A4 Inhibitor Itraconazole or the CYP3A4 Inducer Rifampin on the Pharmacokinetics of Rocbrutinib in Healthy Subjects

Status: Not yet recruiting
Phase of Trial: Phase I

Latest Information Update: 04 Feb 2026

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At a glance

  • Drugs Itraconazole (Primary) ; Rifampicin (Primary) ; Rocbrutinib (Primary)
  • Indications Crohn's disease; Diarrhoea; Inflammatory bowel diseases
  • Focus Pharmacokinetics
  • Sponsors Guangzhou Lupeng Pharmaceutical

Most Recent Events

  • 04 Feb 2026 New trial record

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