Trial Profile

A Phase 1, Open-label, 2-part, Drug-Drug Interaction Study to Evaluate the Effects of Multiple Oral Doses of Rezatapopt on the Pharmacokinetics of Metformin, Rosuvastatin, Repaglinide, and Midazolam in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation.

Status: Not yet recruiting

Phase of Trial: Phase I

Latest Information Update: 04 Feb 2026

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At a glance

Drugs Metformin (Primary) ; Midazolam (Primary) ; Repaglinide (Primary) ; Rezatapopt (Primary) ; Rosuvastatin (Primary)
Indications CNS cancer; Prostate cancer; Solid tumours
Focus Pharmacokinetics
Sponsors PMV Pharmaceuticals

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