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A Dose Escalation Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MK-1045 in Participants With Systemic Lupus Erythematosus and Rheumatoid Arthritis

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Trial Profile

A Dose Escalation Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MK-1045 in Participants With Systemic Lupus Erythematosus and Rheumatoid Arthritis

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 23 Feb 2026

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At a glance

  • Drugs CN 201 (Primary)
  • Indications Rheumatoid arthritis; Systemic lupus erythematosus
  • Focus Adverse reactions
  • Sponsors Merck Sharp & Dohme

Most Recent Events

  • 20 Feb 2026 Status changed from not yet recruiting to recruiting.
  • 04 Feb 2026 New trial record
  • 02 Feb 2026 Planned initiation date changed from 6 Feb 2026 to 27 Feb 2026.

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