Trial Profile

Open-label, Phase I/II Study to Evaluate Safety and Efficacy of Asciminib With Chemotherapy Followed by Asciminib Plus Blinatumomab in Pediatric, Adolescent, and Young Adults With Relapsed or Refractory BCR::ABL1-positive (Philadelphia Positive, Ph+) or BCR::ABL1-like (Ph-like) ALL

Status: Not yet recruiting

Phase of Trial: Phase I/II

Latest Information Update: 10 Feb 2026

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At a glance

Drugs Asciminib (Primary) ; Blinatumomab; Cytarabine; Dexamethasone; Dexamethasone; Hydrocortisone; Methotrexate; Prednisolone; Vincristine
Indications Precursor B-cell lymphoblastic leukaemia-lymphoma; Precursor cell lymphoblastic leukaemia-lymphoma
Focus Adverse reactions; Therapeutic Use
Sponsors Novartis Pharmaceuticals

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