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A Phase 1 Crossover Design Study to Assess the Effect of CYP3A Moderate and Strong Inhibitors (Fluconazole and Itraconazole) and Strong Inducer (Carbamazepine) on the Single-dose Pharmacokinetics of ASP3082 in Healthy Adults

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Trial Profile

A Phase 1 Crossover Design Study to Assess the Effect of CYP3A Moderate and Strong Inhibitors (Fluconazole and Itraconazole) and Strong Inducer (Carbamazepine) on the Single-dose Pharmacokinetics of ASP3082 in Healthy Adults

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 10 Mar 2026

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At a glance

  • Drugs Setidegrasib (Primary) ; Carbamazepine; Fluconazole; Itraconazole
  • Indications Solid tumours
  • Focus Pharmacokinetics
  • Sponsors Astellas Pharma

Most Recent Events

  • 05 Mar 2026 Status changed from not yet recruiting to recruiting.
  • 16 Feb 2026 New trial record

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