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A Phase I/IIa Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity and Preliminary Efficacy of HMPL-A580 in Participants With Advanced or Metastatic Solid Tumors

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Trial Profile

A Phase I/IIa Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity and Preliminary Efficacy of HMPL-A580 in Participants With Advanced or Metastatic Solid Tumors

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 01 Apr 2026

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At a glance

  • Drugs HMPL A 580 (Primary)
  • Indications Solid tumours
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Sponsors HUTCHMED

Most Recent Events

  • 27 Mar 2026 Planned initiation date changed from 1 Mar 2026 to 4 Mar 2026.
  • 04 Mar 2026 According to HUTCHMED media release, company announced that it has initiated this trial in China and the US. The first patient received the first dose on March 4, 2026.
  • 04 Mar 2026 Status changed from not yet recruiting to recruiting.

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