A Phase 3, Randomized, Double-Blind, Active-Controlled Clinical Study to Evaluate the Safety, Tolerability, and Immunogenicity of VAX-31 in Healthy Subjects 50 Years of Age and Older With Prior Pneumococcal Vaccination
Latest Information Update: 20 Mar 2026
At a glance
- Drugs VAX 31 (Primary) ; PCV 20; PPSV-23
- Indications Pneumococcal infections
- Focus Adverse reactions; Pharmacodynamics; Registrational
- Acronyms OPUS-3
- Sponsors Vaxcyte
Most Recent Events
- 18 Mar 2026 According to a Vaxcyte media release, VAX-31 high dose has been advanced into Comprehensive Phase 3 Adult Program on the basis of positive results from Phase 1/2 Study in Adults Aged 50 and Older.
- 17 Feb 2026 New trial record
- 11 Feb 2026 According to an Vaxcyte media release, first participants has been dosed.