Trial Profile

A Phase 1/1b Study Evaluating the Safety, Tolerability, and Pharmacokinetics of AMG 436 as Monotherapy and in Combination With Other Therapies in Participants With Microsatellite Instability-high (MSI-H)/Mismatch Repair Deficient (dMMR) Solid Tumors

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 24 Mar 2026

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At a glance

19 Mar 2026 Planned End Date changed from 23 Apr 2032 to 28 Jun 2028.
19 Mar 2026 Planned primary completion date changed from 23 Apr 2029 to 28 Jun 2028.
19 Mar 2026 Planned initiation date changed from 21 Jan 2026 to 23 Mar 2026.

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