Trial Profile

A Phase 3, Double-blind, Placebo-controlled, Randomized Study to Assess the Efficacy and Safety of ASP3082 in Combination With mFOLFIRINOX or NALIRIFOX as First-line Treatment in Participants With KRAS G12D Mutated Metastatic Pancreatic Adenocarcinoma

Status: Recruiting

Phase of Trial: Phase III

Latest Information Update: 24 Apr 2026

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At a glance

Drugs Fluorouracil (Primary) ; Folinic acid (Primary) ; Irinotecan (Primary) ; Oxaliplatin (Primary) ; Setidegrasib (Primary)
Indications Adenocarcinoma; Pancreatic cancer; Pancreatic ductal carcinoma
Focus Registrational; Therapeutic Use
Sponsors Astellas Pharma

15 Apr 2026 According to Astellas Pharma media release, the first patient has been successfully dosed in this study.
06 Mar 2026 Status changed from not yet recruiting to recruiting.
18 Feb 2026 New trial record

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