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A Phase 3 Multicenter, Open-label Study to Assess the Long-term Safety and Tolerability of KarXT in Adolescents (13 to 17 Years of Age) With Schizophrenia and KarXT+KarX-EC in Children and Adolescents (5 to 17 Years of Age) With Irritability Associated With Autism Spectrum Disorder

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Trial Profile

A Phase 3 Multicenter, Open-label Study to Assess the Long-term Safety and Tolerability of KarXT in Adolescents (13 to 17 Years of Age) With Schizophrenia and KarXT+KarX-EC in Children and Adolescents (5 to 17 Years of Age) With Irritability Associated With Autism Spectrum Disorder

Status: Not yet recruiting
Phase of Trial: Phase III

Latest Information Update: 26 Feb 2026

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At a glance

  • Drugs Trospium chloride/xanomeline (Primary)
  • Indications Autism spectrum disorder; Schizophrenia
  • Focus Adverse reactions; Registrational
  • Sponsors Karuna Therapeutics

Most Recent Events

  • 26 Feb 2026 New trial record

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