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A Phase 1/2 First-in-Human, Open-Label, Dose Escalation and Expansion Trial of TAK-505 Monotherapy in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors

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Trial Profile

A Phase 1/2 First-in-Human, Open-Label, Dose Escalation and Expansion Trial of TAK-505 Monotherapy in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 02 May 2026

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At a glance

  • Drugs TAK 505 (Primary)
  • Indications Adenocarcinoma; Colorectal cancer; Gastric cancer; Head and neck cancer; Mouth neoplasm; Non-small cell lung cancer; Solid tumours; Squamous cell cancer
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Sponsors Takeda

Most Recent Events

  • 23 Apr 2026 Planned initiation date changed from 15 Apr 2026 to 29 Apr 2026.
  • 23 Apr 2026 Status changed from not yet recruiting to recruiting.
  • 04 Mar 2026 New trial record

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