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A Phase 1, Open-label, Single-Dose Study to Evaluate the Pharmacokinetics of AMG 133 in Participants With Varying Degrees of Hepatic Impairment or Normal Hepatic Function

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Trial Profile

A Phase 1, Open-label, Single-Dose Study to Evaluate the Pharmacokinetics of AMG 133 in Participants With Varying Degrees of Hepatic Impairment or Normal Hepatic Function

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 16 Mar 2026

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At a glance

  • Drugs Maridebart cafraglutide (Primary)
  • Indications Atherosclerosis; Heart failure; Obesity; Sleep apnoea syndrome; Type 2 diabetes mellitus
  • Focus Pharmacokinetics
  • Sponsors Amgen

Most Recent Events

  • 11 Mar 2026 Status changed from active, no longer recruiting to completed.
  • 05 Mar 2026 New trial record

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