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A Phase I, Multicenter, Open-Label, Multiple-Ascending Dose Study of the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 Administered by Intravitreal Injection as Monotherapy and in Combination With Faricimab in Patients With Diabetic Macular Edema

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Trial Profile

A Phase I, Multicenter, Open-Label, Multiple-Ascending Dose Study of the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 Administered by Intravitreal Injection as Monotherapy and in Combination With Faricimab in Patients With Diabetic Macular Edema

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 24 Mar 2026

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At a glance

  • Drugs Faricimab (Primary) ; RO 7823653 (Primary)
  • Indications Diabetic macular oedema
  • Focus Adverse reactions
  • Sponsors Genentech

Most Recent Events

  • 19 Mar 2026 Status changed from not yet recruiting to recruiting.
  • 05 Mar 2026 New trial record

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