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An Open-label, Multicenter Phase I/II Clinical Study to Evaluate the Safety, Tolerance, Pharmacokinetics and Anti-tumor Activity of JMKX001899 Tablets in Patients with Advanced or Metastatic Solid Tumors Harboring KRAS G12C Mutation (Phase Ia) and Patients with Non-small Cell Lung Cancer (Phase Ib, II)

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Trial Profile

An Open-label, Multicenter Phase I/II Clinical Study to Evaluate the Safety, Tolerance, Pharmacokinetics and Anti-tumor Activity of JMKX001899 Tablets in Patients with Advanced or Metastatic Solid Tumors Harboring KRAS G12C Mutation (Phase Ia) and Patients with Non-small Cell Lung Cancer (Phase Ib, II)

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 09 Mar 2026

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At a glance

  • Drugs Sosimerasib (Primary)
  • Indications Non-small cell lung cancer; Solid tumours
  • Focus Adverse reactions; Registrational; Therapeutic Use

Most Recent Events

  • 09 Mar 2026 New trial record

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