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Onasemnogene Abeparvovec: ASsessing The REAl-world Safety & Effectiveness of Spinal Muscular Atrophy Participants Treated With Intrathecal Onasemnogene Abeparvovec-brve (ITVISMA®): A U.S. Pragmatic Multicenter Study (STREAM)

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Trial Profile

Onasemnogene Abeparvovec: ASsessing The REAl-world Safety & Effectiveness of Spinal Muscular Atrophy Participants Treated With Intrathecal Onasemnogene Abeparvovec-brve (ITVISMA®): A U.S. Pragmatic Multicenter Study (STREAM)

Status: Not yet recruiting
Phase of Trial: Phase IV

Latest Information Update: 07 Apr 2026

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At a glance

  • Drugs Onasemnogene abeparvovec (Primary)
  • Indications Spinal muscular atrophy
  • Focus Therapeutic Use
  • Acronyms STREAM
  • Sponsors Novartis Pharmaceuticals

Most Recent Events

  • 18 Mar 2026 Planned End Date changed from 1 Apr 2034 to 30 Jun 2032.
  • 09 Mar 2026 New trial record

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