Trial Profile

A Phase 1b Clinical Trial of AKL003, an Alpha Klotho mRNA Therapeutic, for the Extension of Human Lifespan

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 11 Mar 2026

Price :

$35 ^*

Note:

Adis is an information provider.
Final gross price and currency may vary according to local VAT and billing address.
Your purchase entitles you to full access to the information contained in our trial profile at the time of purchase.
A link to download a PDF version of the trial profile will be included in your email receipt.

At a glance

Drugs AKL 003 (Primary)
Indications Metabolic syndrome
Focus Adverse reactions

Most Recent Events

11 Mar 2026 New trial record
19 Feb 2026 According to Klothea Bio media release, the company expects to provide an update on first participant dosed in the coming weeks, subject to enrollment progress and study procedures.
19 Feb 2026 According to Klothea Bio media release, Douglas Tucker, M.D. is a principal investigator.

You need to be a logged in or subscribed to view this content

If your organization or you do not have a subscription, try one of the following:

Contacting your organization’s admin about adding this content to your AdisInsight subscription
Buying a PDF version of any individual profile
Request a free trial (opens in a new window)

If your organization has a subscription, there are several access options, even while working remotely:

Working within your organization’s network
Login with username/password or try to access via your institution
Persisted access using your organization’s identifier stored in your user browser for 90 days

For assistance, contact us at asktheexpert.adisinsight@springer.com