Trial Profile

A First-in-human Phase 1 Dose-escalation Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of KST-6051 in Patients With Advanced or Metastatic Solid Tumors With a KRAS Mutation

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 17 Apr 2026

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At a glance

Drugs KST 6051 (Primary)
Indications Adenocarcinoma; Colorectal cancer; Non-small cell lung cancer; Pancreatic ductal carcinoma; Solid tumours
Focus Adverse reactions; First in man
Acronyms FALCON
Sponsors Kestrel Therapeutics

24 Mar 2026 The protocol has been amended to change interventional study model as Sequential Assignment
24 Mar 2026 Status changed from not yet recruiting to recruiting.
17 Mar 2026 New trial record

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