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Post-transplant Optimization Based on Ultra-high Sensitivity MRD Detection: A Prospective, Randomized Controlled Study Comparing Gilteritinib Versus Sorafenib as Post-transplant Maintenance Therapy in FLT3-ITD Mutation-positive Acute Myeloid Leukemia Patients

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Trial Profile

Post-transplant Optimization Based on Ultra-high Sensitivity MRD Detection: A Prospective, Randomized Controlled Study Comparing Gilteritinib Versus Sorafenib as Post-transplant Maintenance Therapy in FLT3-ITD Mutation-positive Acute Myeloid Leukemia Patients

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 24 Mar 2026

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At a glance

  • Drugs Gilteritinib (Primary) ; Sorafenib
  • Indications Acute myeloid leukaemia
  • Focus Therapeutic Use
  • Acronyms TROPHY-15

Most Recent Events

  • 20 Mar 2026 Status changed from not yet recruiting to recruiting.
  • 17 Mar 2026 New trial record

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