Trial Profile

DAREON -Lung-1: A Phase III Multi-center, Open-label, Randomised Trial of Intravenous Obrixtamig in Combination With Atezolizumab, Carboplatin, and Etoposide vs. Atezolizumab, Carboplatin, and Etoposide as First-line Treatment in Patients With Extensive-stage Small Cell Lung Cancer

Status: Recruiting

Phase of Trial: Phase III

Latest Information Update: 14 May 2026

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At a glance

Drugs Atezolizumab (Primary) ; Carboplatin (Primary) ; Etoposide (Primary) ; Obrixtamig (Primary)
Indications Small cell lung cancer
Focus Registrational; Therapeutic Use
Acronyms DAREON -Lung-1
Sponsors Boehringer Ingelheim

20 Apr 2026 Planned End Date changed from 31 Jul 2029 to 30 Jul 2029.
20 Apr 2026 Planned primary completion date changed from 10 Sep 2028 to 9 Sep 2028.
20 Apr 2026 Status changed from not yet recruiting to recruiting.

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