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DAREON -Lung-1: A Phase III Multi-center, Open-label, Randomised Trial of Intravenous Obrixtamig in Combination With Atezolizumab, Carboplatin, and Etoposide vs. Atezolizumab, Carboplatin, and Etoposide as First-line Treatment in Patients With Extensive-stage Small Cell Lung Cancer

Trial Profile

DAREON -Lung-1: A Phase III Multi-center, Open-label, Randomised Trial of Intravenous Obrixtamig in Combination With Atezolizumab, Carboplatin, and Etoposide vs. Atezolizumab, Carboplatin, and Etoposide as First-line Treatment in Patients With Extensive-stage Small Cell Lung Cancer

Status: Not yet recruiting
Phase of Trial: Phase III

Latest Information Update: 15 Apr 2026

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At a glance

  • Drugs Atezolizumab (Primary) ; Carboplatin (Primary) ; Etoposide (Primary) ; Obrixtamig (Primary)
  • Indications Small cell lung cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms DAREON -Lung-1
  • Sponsors Boehringer Ingelheim

Most Recent Events

  • 31 Mar 2026 Planned End Date changed from 16 Apr 2029 to 31 Jul 2029.
  • 22 Mar 2026 New trial record

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