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Phase 3 Single-Arm Open-Label Study to Evaluate the Efficacy and Safety of Zodasiran in Adolescent Participants (Age 12 to <18 Years) With Homozygous Familial Hypercholesterolemia (SPRUCE)

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Trial Profile

Phase 3 Single-Arm Open-Label Study to Evaluate the Efficacy and Safety of Zodasiran in Adolescent Participants (Age 12 to <18 Years) With Homozygous Familial Hypercholesterolemia (SPRUCE)

Status: Not yet recruiting
Phase of Trial: Phase III

Latest Information Update: 23 Mar 2026

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At a glance

  • Drugs Zodasiran (Primary)
  • Indications Hyperlipoproteinaemia type IIa
  • Focus Registrational; Therapeutic Use
  • Acronyms SPRUCE
  • Sponsors Arrowhead Pharmaceuticals

Most Recent Events

  • 23 Mar 2026 New trial record

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