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A Phase I Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetic Characteristics of HLX48 (EGFR/c-MET Bispecific Antibody-Drug Conjugate) in Participants With Advanced/Metastatic Solid Tumors

Trial Profile

A Phase I Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetic Characteristics of HLX48 (EGFR/c-MET Bispecific Antibody-Drug Conjugate) in Participants With Advanced/Metastatic Solid Tumors

Status: Not yet recruiting
Phase of Trial: Phase I

Latest Information Update: 30 Apr 2026

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At a glance

  • Drugs HLX 48 (Primary)
  • Indications Liver cancer; Solid tumours
  • Focus Adverse reactions; First in man
  • Sponsors Shanghai Henlius Biotech

Most Recent Events

  • 23 Apr 2026 According to a Shanghai Henlius Biotech media release, investigational new drug (IND) application for HLX48 has been accepted by the Center for Drug Evaluation (CDE) of the National Medical Products Administration (NMPA) in China and has also been filed with Australia's Therapeutic Goods Administration (TGA).
  • 23 Mar 2026 New trial record

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