H&N NEO-COMBAT XL: Neoadjuvant XL-092 (Zanzalintinib) and Pembrolizumab (Keytruda) in Surgically Resectable, HPV Negative Oral Cavity Squamous Cell Carcinoma (OCSCC)
Latest Information Update: 27 May 2026
At a glance
- Drugs Pembrolizumab (Primary) ; Zanzalintinib (Primary)
- Indications Head and neck cancer; Squamous cell cancer
- Focus Therapeutic Use
- Acronyms H&N NEO-COMBAT XL
Most Recent Events
- 08 May 2026 Planned initiation date changed from 1 May 2026 to 1 Jun 2026.
- 24 Mar 2026 New trial record