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H&N NEO-COMBAT XL: Neoadjuvant XL-092 (Zanzalintinib) and Pembrolizumab (Keytruda) in Surgically Resectable, HPV Negative Oral Cavity Squamous Cell Carcinoma (OCSCC)

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Trial Profile

H&N NEO-COMBAT XL: Neoadjuvant XL-092 (Zanzalintinib) and Pembrolizumab (Keytruda) in Surgically Resectable, HPV Negative Oral Cavity Squamous Cell Carcinoma (OCSCC)

Status: Not yet recruiting
Phase of Trial: Phase II

Latest Information Update: 24 Mar 2026

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At a glance

  • Drugs Pembrolizumab (Primary) ; Zanzalintinib (Primary)
  • Indications Head and neck cancer; Squamous cell cancer
  • Focus Therapeutic Use
  • Acronyms H&N NEO-COMBAT XL

Most Recent Events

  • 24 Mar 2026 New trial record

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