TACE or Ablation Combined With Sintilimab and Ipilimumab N01 as Neoadjuvant Therapy for Resectable Hepatocellular Carcinoma With Intermediate-High Recurrence Risk: A Multicenter, Multigroup, Randomized, Phase ??? Exploratory Clinical Trial
Latest Information Update: 11 Apr 2026
At a glance
- Drugs Ipilimumab (Primary) ; Lenvatinib (Primary) ; Sintilimab (Primary)
- Indications Liver cancer
- Focus Therapeutic Use
- Acronyms ACTION-001
Most Recent Events
- 30 Mar 2026 New trial record
- 27 Mar 2026 Number of treatment arms are increased from 4 to 5 by the addition of "No Intervention: Surgery alone". Planned enrollment is also increased.
- 27 Mar 2026 Planned number of patients changed from 90 to 105.