Trial Profile

A Phase 1b-2, Open-Label, Dose-Escalation, Expansion and Optimization Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of LRK-4189 Alone and in Combination With mFOLFOX6 or FOLFIRI in Patients With Solid Tumors

Status: Not yet recruiting

Phase of Trial: Phase I/II

Latest Information Update: 30 Mar 2026

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At a glance

Drugs LRK 4189 (Primary) ; Fluorouracil; Folinic acid; Irinotecan; Oxaliplatin
Indications Colorectal cancer; Solid tumours
Focus Adverse reactions
Sponsors Larkspur Biosciences

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