Trial Profile

Beamion 44: A Randomized, Open-label, Multi-center Phase IIa Platform Trial to Evaluate the Safety and Tolerability of Zongertinib Plus Platinum-based Doublet Chemotherapy With or Without Pembrolizumab (and Potential Other Combinations) in Treatment-naïve Patients With Locally Advanced/Metastatic Non-squamous NSCLC With Activating HER2 Mutations

Status: Not yet recruiting

Phase of Trial: Phase II

Latest Information Update: 31 Mar 2026

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At a glance

Drugs Carboplatin (Primary) ; Cisplatin (Primary) ; Pembrolizumab (Primary) ; Pemetrexed (Primary) ; Zongertinib (Primary)
Indications Non-small cell lung cancer
Focus Adverse reactions
Sponsors Boehringer Ingelheim

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