Trial Profile

A Phase 1/2, Open-label, Biomarker-guided, Dose-escalation and Expansion Study of Dual-targeting CAR-NK Cells Directed Against Mesothelin (MSLN) and MUC1, With an Exploratory CLDN18.2/MUC1 Dual-target Cohort, in Patients With Unresectable or Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 31 Mar 2026

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At a glance

Drugs Cyclophosphamide (Primary) ; EB DNK 101 (Primary) ; EB DNK 102 (Primary) ; Fludarabine (Primary)
Indications Adenocarcinoma; Pancreatic ductal carcinoma
Focus Adverse reactions
Acronyms DUAL-NK-PDAC
Sponsors Beijing BioTech

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