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A Phase 2 proof-of-concept study of SCY-770 in Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Trial Profile

A Phase 2 proof-of-concept study of SCY-770 in Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Status: Planning
Phase of Trial: Phase II

Latest Information Update: 15 Oct 2026

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At a glance

  • Drugs SCY 770 (Primary)
  • Indications Autosomal dominant polycystic kidney disease
  • Focus Proof of concept; Therapeutic Use

Most Recent Events

  • 06 Oct 2026 According to SCYNEXIS media release, Pharmacokinetic data from phase 1 study and prior studies will inform dose selection for the Phase 2 trial in patients with ADPKD, which remains on track to initiate in the fourth quarter of 2026.
  • 28 Sep 2026 According to SCYNEXIS media release, The Company does not anticipate any changes to its previously communicated guidance regarding development milestones for SCY-770, its lead product candidate for Autosomal Dominant Polycystic Kidney Disease (ADPKD), or the Companys cash runway into 2029.
  • 10 Aug 2026 According to SCYNEXIS media release, the company remains on track to initiate the trial in Q4 2026, with an anticipated early efficacy readout in the second half of 2027.

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