Trial Profile

A Two-Part, Phase 2a, Randomized, Double-Blind, Placebo-Controlled Study of ALN-PNP With and Without a GLP1R Agonist in Adults With Homozygous PNPLA3-Related Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Status: Not yet recruiting

Phase of Trial: Phase II

Latest Information Update: 20 Apr 2026

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At a glance

Drugs ALN PNP (Primary) ; Tirzepatide (Primary)
Indications Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis
Focus Therapeutic Use
Sponsors Regeneron Pharmaceuticals

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