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Phase 1-2, Open-Label, Single and Multiple Ascending Dose Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION337 in Patients With Dravet Syndrome

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Trial Profile

Phase 1-2, Open-Label, Single and Multiple Ascending Dose Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION337 in Patients With Dravet Syndrome

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 06 May 2026

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At a glance

  • Drugs ION 337 (Primary)
  • Indications Dravet syndrome
  • Focus Adverse reactions
  • Acronyms ASCEND
  • Sponsors Ionis Pharmaceuticals

Most Recent Events

  • 21 Apr 2026 Status changed from not yet recruiting to recruiting.
  • 21 Apr 2026 New trial record

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