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A Phase 1, Open-Label, Fixed-Sequence Study to Evaluate the Effects of Multiple Doses of Itraconazole on the Single-Dose Pharmacokinetics of MK-5684 in Healthy Adult Male Participants

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Trial Profile

A Phase 1, Open-Label, Fixed-Sequence Study to Evaluate the Effects of Multiple Doses of Itraconazole on the Single-Dose Pharmacokinetics of MK-5684 in Healthy Adult Male Participants

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 01 Jul 2026

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At a glance

  • Drugs Opevesostat (Primary) ; Fludrocortisone; Itraconazole; Prednisone
  • Indications Breast cancer; Endometrial cancer; Ovarian cancer; Prostate cancer
  • Focus Pharmacokinetics
  • Sponsors Merck Sharp & Dohme

Most Recent Events

  • 25 Jun 2026 Status changed from active, no longer recruiting to completed.
  • 26 May 2026 Status changed from recruiting to active, no longer recruiting.
  • 30 Apr 2026 Status changed from not yet recruiting to recruiting.

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