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A Phase 1/1b dose escalation and expansion trial designed to evaluate the safety, tolerability, immunogenicity, and early clinical activity of CryptiVax™-1001 in HRP+/BRCA-wildtype high-grade serous ovarian cancer

Trial Profile

A Phase 1/1b dose escalation and expansion trial designed to evaluate the safety, tolerability, immunogenicity, and early clinical activity of CryptiVax™-1001 in HRP+/BRCA-wildtype high-grade serous ovarian cancer

Status: Planning
Phase of Trial: Phase I

Latest Information Update: 29 Apr 2026

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At a glance

  • Drugs MRNA-based-vaccine-Epitopea (Primary)
  • Indications Ovarian cancer
  • Focus Adverse reactions; First in man
  • Acronyms OVACT

Most Recent Events

  • 29 Apr 2026 New trial record
  • 23 Apr 2026 According to Epitopea media release, Professor Susana Banerjee is the Chief Investigator of the OVACT trial.
  • 23 Apr 2026 According to Epitopea media release, company announced that it has received approval from the UK Medicines and Healthcare products Regulatory Agency (MHRA) and the Regional Ethics Committee (REC) for its clinical trial application (CTA) for its first-in-human clinical trial (OVACT) of its lead program, CryptiVax-1001, targeting advanced high-grade serous ovarian cancer.

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