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Randomized, Double-Blinded, Vehicle-Controlled, Parallel Group, Adaptive Proof-of-concept, Dose-selecting Phase 2a Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of Intranasal Cenegermin (recombinant human Nerve Growth Factor [rhNGF]) in Adult Participants with subacute moderate to severe Traumatic Brain Injury (TBI). - NGF-TBI-201

Trial Profile

Randomized, Double-Blinded, Vehicle-Controlled, Parallel Group, Adaptive Proof-of-concept, Dose-selecting Phase 2a Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of Intranasal Cenegermin (recombinant human Nerve Growth Factor [rhNGF]) in Adult Participants with subacute moderate to severe Traumatic Brain Injury (TBI). - NGF-TBI-201

Status: Not yet recruiting
Phase of Trial: Phase II

Latest Information Update: 04 May 2026

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At a glance

  • Drugs Cenegermin (Primary)
  • Indications Traumatic brain injuries
  • Focus Adverse reactions; Proof of concept
  • Sponsors Dompe Farmaceutici

Most Recent Events

  • 04 May 2026 New trial record

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